Jacksonville Jaguars – Indianapolis Colts

NFL American football, played over four quarters, at EverBank Stadium. Jacksonville hosts Indianapolis on November 1, 2026 at 18:00 UTC, a time confirmed by official schedules.

The Jaguars are coming off a bye after two road games, while the Colts go from a trip to Minnesota to Jacksonville without an immediate bye. The recent quality of opponents and advanced unit statistics are not established.

Recent head-to-head matchups between Jacksonville and Indianapolis are not established in the verified materials. Their predictive value therefore cannot be assessed here.

Anton Harrison was placed on Jacksonville’s injured reserve list on October 13, 2026. Antonio Johnson, Montaric Brown, and Ross Matiscik were subject to uncertainty, with no confirmed detailed game status.

The Colts’ full report has not been verified; the statuses of Anthony Richardson, Jonathan Taylor, the offensive line, and the key defenders remain unknown.

The favorable scenario for Jacksonville rests on home-field advantage, the bye, and superior preparation, but recent international travel and uncertainty surrounding protection could reduce this advantage. The favorable scenario for Indianapolis rests on possible Jacksonville fatigue and defensive limitations on the home side, but the Colts are playing away without a bye, and their own absences are unknown.

The weather, surface, and official inactives remain to be confirmed.

The starters and final inactive players have not yet been confirmed. The composition of the offensive and defensive lines remains unknown for both teams.

Prediction: Jacksonville Jaguars · Match winner. Estimated probability: 80.7 %, based on market odds. No stake: this probability does not justify a bet at the available odds.