Washington Commanders – Indianapolis Colts

Washington is coming off a 33–31 win over Seattle on September 27 after losses to Philadelphia and Dallas. Indianapolis beat Houston 19–17 after losses to Baltimore and Kansas City, the latter in overtime.

The comparative strength of the opponents, efficiency per play, and advanced statistics do not allow for a clear separation between the two forms.

No recent documented head-to-head matchup is established in the selected materials. The absence of a verified history here prevents drawing a predictive advantage from it; the international context and current form are more directly relevant.

NFL regular-season game, Week 4, at Tottenham Hotspur Stadium in London, with 11 players per team on the field and four quarters. Both teams are coming off Week 3 and must manage international travel, with no confirmed acclimatization advantage.

Washington scenario: the defense can still compensate for a potential absence of Daniels if it forces turnovers, but this effect depends on turnovers that are difficult to repeat. Indianapolis scenario: Daniels’ absence would potentially allow the Colts to focus their defense on passing reads and the ground game, but the Week 3 absences and the quality of the Colts’ units remain insufficiently documented.

Provided schedule: October 4, 2026 at 09:30 EDT, i.e. 14:30 in London.

The full list of starters has not been confirmed. Marcus Mariota had been announced as Washington’s starter in Week 3, without confirmation for London.

The roles of Jonathan Taylor and Daniel Jones are presented as Colts reference points, without any guarantee regarding their presence or role on October 4.

Selection: Under 47.5 points (Totals). Estimated probability: 50.8%, based on market odds. Odds 1.962. No bet: this probability is not sufficient to justify a wager at these odds.