Buffalo Bills – Los Angeles Chargers

Buffalo is 2–0 after wins over Houston (36–31) and Detroit (41–31), with 77 points scored across those two games. Josh Allen produced five touchdowns against Detroit, and Dalton Kincaid totaled 225 receiving yards over the first two weeks.

Los Angeles is 0–2 after two identical defeats, 14–26 against Arizona and then Las Vegas. Against the Raiders, the Chargers limited the rushing game to 57 yards but allowed passing gains of 40, 42 and 27 yards and committed three turnovers.

These figures cover only two games per team, and the detailed quality of opposition remains limited.

The Chargers’ official page indicates a favorable overall history for Los Angeles of 25–14–2. The recent documented meetings with a date or season and score are: information unavailable.

This aggregate history is old or not detailed and does not directly measure the form of the two teams in 2026.

Buffalo plays at Highmark Stadium, on natural grass reseeded in early September after density issues; the weather conditions and the exact state of the field on game day are unknown. The Bills are playing their third consecutive home game and benefit from more rest after playing on Thursday, 17 September, while the Chargers played on Sunday, 20 September, before traveling to Buffalo.

Favorable scenario for Buffalo: Allen and Kincaid exploit the explosive passes recently conceded by Los Angeles, with the field and rest providing support. Favorable scenario for Los Angeles: Herbert maintains an offensive threat and the defense limits the running game as against Las Vegas; a reduction in turnovers and possession errors could allow a rebound despite starting 0–2.

The weather, inactives, and starting lineups remain unknown.

The game is an NFL regular-season matchup, Week 3, between Buffalo Bills and Los Angeles Chargers, with two teams of 11 players and four quarters of 15 minutes. Buffalo hosts Los Angeles at Highmark Stadium on 27 September 2026 at 13 h EDT, or 17 h UTC.

The starting lineups, the five linemen, and the receiver groups are not confirmed.